In 2019, the national Medical Council revoked her medical license and ordered her to stop working as a (sexy) model and made sure she couldn't work as a doctor again when she didn't. Her sexually charged photos led the malaria monitoring and evaluation office in Yangon, where she worked as a medical officer, to demand her resignation. She has appeared in several television advertisements including OK Dollar, Biomanic Plus and other commercials. She began posting sexually charged photos in swimwear and lingerie on social media as a hobby, drawing an audience and commercial appearances. She worked as a medical officer for local hospitals and NGO's in Shan, Kachin, and Rakhine States, including in displaced camps for the Rohingya Muslims. She became a trained physician at the age of 22. After passing her matriculation exam with flying colours, she entered the University of Medicine 1, Yangon. She attended high school at Basic Education High School No.

Her father Sai San Win, was a medical doctor who served as a deputy project medical coordinator at Médecins Sans Frontières, and mother Kyu Kyu Swe, is also a physician.

Nang Mwe San was born on 23 June 1988 in Kunhing, Shan State, Myanmar into a medical family. She is said to have become the first person imprisoned in Myanmar for content on OnlyFans after being sentenced to six years in prison. On 5 August 2022, in the aftermath of the 2021 Myanmar coup d'état, she was arrested by the military junta under Section 33(a) of Electronic Law for earning money by accused of harming Myanmar culture and posting sexually revealing photos on the websites OnlyFans and Exantria, along with Thinzar Wint Kyaw, a popular actress and sexy model. In July 2020, she was appointed Kindness Ambassador of YVCT College. She is featured in The Irrawaddy's 'Top Myanmar Sexy Models' list in 2020. She is considered as the country's most famous sexy model, according to The Myanmar Times. Nang Mwe San ( Burmese: နန်းမွေစံ born 23 June 1988) is a Burmese model and former medical doctor.

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